ITGA2 anticorps (AA 25-75)
Aperçu rapide pour ITGA2 anticorps (AA 25-75) (ABIN7453111)
Antigène
Voir toutes ITGA2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 25-75
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Fonction
- Rabbit anti-ITGA2 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- Between AA 25 and 75
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Isotype
- IgG
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Indications d'application
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- ITGA2 (Integrin alpha 2 (ITGA2))
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Autre désignation
- ITGA2/CD49B/Integrin alpha-2
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Sujet
- Background: Integrin alpha-2 is product of the gene ITGA2 (aka CD49B). Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. This receptor mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia [taken from NCBI Entrez Gene (Gene ID: 3673) and UniProtKB (Entry: P17301)].
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ID gène
- 3673
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UniProt
- P17301
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Pathways
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
Antigène
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